Electrochemistry VI

In organic chemistry the strategic steps in complex syntheses are bond forming reactions. Therefore, as mature method, electroorganic has to compete with the powerful repertoire of alternative synthetic processes which have been developed for this pupose in recent years. The volume Electrochemistry VI of Topics in Current Chemistry reviews the state of the art of modern bond forming reactions at the anode and cathode, demonstrating that they continue to be highly competitive with alternative methods. It highlights both the current value and the large potential of organic electrochemistry for the selective formation of carbon-carbon and carbon-heteroatom bonds and for the generation of complex organic molecules using electrochemical key steps. The utility of electrochemistry for the generation of highly reactive intermediates under mild conditions and for the selective reversal of the polarity of functional groups is demonstrated for ring forming reactions and carbon-carbon cross-coupling reactions. The contents range from the synthesis of natural products to the preparation of pharmaceuticals, from the generation of unsymmetrical biaryls to the construction ofpeptide mimetics. The electrochemical prodedures are critically compared with alternative chemical processes and mechanistic considerations are included.