More than forty years ago the then major honchos of molecular biology published a festschrift for Max Delbr?uck, lauding, in a self-congratulatory but often delightful and enthusiastic way, the central role bacteriophages played in the development of molecular biology (Cairns, J., G. Stent, and J. Watson. 1966. Phage and the Origins of Molecular Biology. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory). The prominence of bacteriophages as model systems for studying molecular biology has since waned. However, even in these days where genetics is rarely done by allowing organisms to move genes by themselves (horror, mating between the unmarried?), bacteriophages maintain a major rep as tools for studies of the genetics and molecular biology of bacteria.
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